Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response
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The labile iron pool in the cell is required for ferroptosis, a form of regulated cell death resulting from excessive lipid peroxidation and membrane damage. Glutathione (GSH) is critical for lipid-peroxide scavenging, and cysteine is the rate-limiting amino a... ...
