MicroRNA-138 regulation promotes the efficacy of oncolytic herpes virus G47Δ for malignant brain tumor therapy
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G47Δ, a third-generation oncolytic herpes simplex virus type 1, is a promising therapeutic agent for malignant glioma. We investigated whether inhibition of host microRNA-138 (miR-138), a regulator of the viral immediate-early protein ICP0, could enhance its ... ...
