Down-Regulation of Hepatic PPA1 Protects Against Obesity by Elevating FGF21 Production via eIF2α Phosphorylation
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Pyrophosphatase 1 (PPA1) is upregulated in livers of high-fat diet-induced obese mice and metabolic dysfunction-associated steatotic liver disease patients. Hepatic PPA1 deletion protects mice against high-fat diet-induced obesity and related metabolic disorde... ...
