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Redefining the role of chaperones for Dot/Icm T4BSS-mediated substrate translocation by Legionella pneumophila

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Legionella pneumophila, the etiological agent of legionnaires' disease, establishes its intracellular niche through the Dot/Icm type IVB secretion system, which translocates ∼300 effector proteins into host cells. Efficient secretion of many effectors requir... ...