Integrated computational screen and validation of thalidomide-based PROTACs targeting SARS-CoV-2 main protease
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The persistent evolution of SARS-CoV-2 underscores the need for antiviral strategies. The viral main protease (Mpro) represents a conspicuous target due to its essential role in viral replication and high conservation across SARS-CoV-2. Conventional Mpro inhib... ...
