Robustness of LETd-optimized multi-ion therapy against range and setup uncertainties: evaluation and enhancement with carbon-, oxygen-, and neon-ion beams
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The LET trilemma-an inherent conflict between target dose homogeneity, range robustness, and high dose-averaged linear energy transfer (LETd)-poses a major challenge in treatment optimization. To ensure accurate beam delivery in multi-ion therapy, this study e... ...
