Microenvironmental TGF-β is an early driver of NF1-associated tumor formation
{{output}}
Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome characterized by neurofibromas, Nf1-/- Schwann cell (SC)-derived tumors of peripheral nerves. We and others have shown that Nf1 loss in SCs is insufficient for neurofibroma formation but ... ...
