Schwann cell-derived extracellular vesicles inhibit osteoclastogenesis through the PTEN/AKT axis in peripheral nerve-bone crosstalk
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Osteoclasts, the sole bone-resorbing cells, play a central part in bone homeostasis, and their overactivation is implicated in bone diseases such as osteoporosis. Schwann cells (SCs), the primary glial cells of the peripheral nervous system, are recognized to ... ...
