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Low-Dose Galactose Rebalances HBP-mTORC1-SREBP-1c Signaling to Suppress Hepatic Lipogenesis and Protect Against Early-Stage Alcohol-Related Liver Disease

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Overactivation of hepatic de novo lipogenesis (DNL) contributes to fatty liver disease. While glucose and fructose strongly promote DNL, diary-rich galactose is only weakly lipogenic. However, whether and how it regulates hepatic DNL remains unclear. In this s... ...