GLP-1, Pancreatic β-Cells, and Insulin Secretion: What We Know and Where We Need to Go
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GLP-1 and its analogs enhance insulin secretion, but the specific intracellular mechanisms in β-cells remain unclear. Key intracellular mediators including calcium, glutamate, γ-aminobutyric acid, serotonin, and urocortin-3 are modulated by GLP-1 signaling w... ...
