Novel pyrimido[1,2- a]imidazole derivatives as potent Pks13-TE inhibitors: structure-based virtual screening and rational design
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Tuberculosis (TB) remains a major global health threat, exacerbated by the emergence of drug-resistant strains. The mycobacterial enzyme Pks13 has emerged as a promising drug target for novel anti-TB agents. We herein report the design, synthesis, and biologic... ...
