Loss of SeqA confers low-level fluoroquinolone resistance through transcriptional reprogramming and RpoS dependence in E. coli
{{output}}
SeqA is a key regulator of DNA replication initiation and chromosome cohesion in Escherichia coli. Loss of SeqA causes replication asynchrony, segregation defects, and growth delay, but its role in antibiotic susceptibility has remained unclear. Fluoroquinolon... ...
