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Kinetic modelling and evaluation of the TrkA/B/C radioligand [18F]TRACK in the pig brain

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Tropomyosin receptor kinase B (TrkB) is a critical mediator of neuronal growth, survival, and synaptic plasticity, which is activated by the endogenous ligand, brain-derived neurotrophic factor (BDNF). TrkB has been implicated in a wide range of neurological c... ...