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Synthesis and Evaluation of Radioiodinated [125I]7-Iodo-5H-Pyrido[4,3-B]Indole ([125I]CTAU) in Postmortem Human Alzheimer's Disease Brain

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The aim of this study was to further understand the tau imaging agent, flortaucipir (T807), by making small modifications and assess its effect on tau protein binding in Alzheimer's disease (AD). Thus, the fluoropyridyl group in T807 was replaced with an iodi... ...