Design, synthesis of 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole derivatives as potential anticancer agents
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The tetrahydro-β-carboline (THβC) scaffold is a promising chemotype in anticancer drug discovery whose development is hindered by poor aqueous solubility and underexplored functionalization at the N-2 position. To overcome these limitations, we designed a se... ...
