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IGF-1 regulates PEAR1 through Egr1 to Promote Skeletal Muscle Post-injury Regeneration

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Insulin-like growth factor 1 (IGF-1) is a key regulator of skeletal muscle growth and regeneration. In this study, we demonstrate that IGF-1 promotes C2C12 myoblast proliferation in a dose- and time-dependent manner. Mechanistically, IGF-1 induces the expressi... ...