Metabolic and Immunomodulatory Effects of α-Ketoglutarate in Burn Injuries: A Systematic Review
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Severe burns unleash a hyper-catabolic and immunosuppressive state that erodes lean tissue and delays repair. Alpha-ketoglutarate (α-KG), usually delivered enterally as the dipeptide ornithine α-ketoglutarate, feeds the tricarboxylic-acid cycle, donates nitr... ...