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MBD3 deficiency decommissions the NuRD complex and orchestrates the epigenetic regulation of gene expression to suppress neuroblastoma progression

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Background: Neuroblastoma (NB) is the most common extracranial solid tumor in children and accounts for 15% of childhood cancer death. The nucleosome remodeling and deacetylase (NuRD) complex is a major chromatin remodeling compl... ...