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Astrocytic SIRT3 Alleviates Neuroinflammatory Responses After Cerebral Ischemia/reperfusion by Inhibiting the cGAS-STING Pathway

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Ischemic stroke triggers detrimental neuroinflammatory responses where astrocytes play a pivotal role. This study investigates whether Sirtuin 3 (SIRT3), a key cellular regulator, mitigates astrocyte-mediated neuroinflammation by modulating the cGAS-STING path... ...