The LXRβ/NF-κB axis reprograms CAR-T cells to resist exhaustion in the tumor microenvironment
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Liver X receptor β (LXRβ) is a key transcription factor involved in lipid metabolism and immune regulation, yet its functional role in tumor-infiltrating T cells remains largely unresolved. While LXRβ has been shown to suppress NF-κB target gene expression... ...
