Safety of Low Dose Inpatient Zoledronic Acid in Acute Hip Fracture Patients with Advanced Chronic Kidney Disease
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Zoledronic acid (ZA), cleared renally, carries a higher nephrotoxicity risk at doses≥4 mg, especially in patients with chronic kidney disease (CKD). While 5 mg is standard for osteoporosis, ZA increases bone mineral density at doses as low as 0.25 mg every 3 ... ...