Optimization of cefepime dosage regimens for Pseudomonas aeruginosa infections in Japanese patients based on a pharmacokinetic/ pharmacodynamic analysis considering efficacy and safety: Is a 6 g daily dose and continuous infusion necessary?
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In Japan, the approved maximum daily dose of cefepime (4 g) is lower than international standards (6 g), potentially compromising efficacy against Pseudomonas aeruginosa (P. aeruginosa) infections. Using Monte Carlo simulations with a population pharmacokineti... ...
