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Runaway uncoupling in 2,4-dinitrophenol poisoning: Clinical and mitochondrial observations from two cases

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2,4-Dinitrophenol (DNP) is a potent mitochondrial uncoupler briefly marketed in the 1930s as a weight-reducing agent before being banned by the FDA after reports of severe toxicity. Since the early 2000s, DNP has reemerged as an illicit "fat-burner", causing... ...