Defective I1 dynein in Chlamydomonas axonemes is epistatic to the RII-binding domain function of radial spoke protein 3 (RSP3) in the regulation of ciliary motility
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In Chlamydomonas , the central pair (CP) and radial spoke (RS) complexes in the axoneme are key regulators of ciliary motility. Radial spoke protein 3 (RSP3) is an A-kinase anchoring protein (AKAP), and mutation of the RII-binding domain ( 388 ) results in spe... ...