Enhanced Lincomycin Titer Through Knockout of GntR Family Regulator SLCG_2790 Combined With Fermentation Optimization in an Industrial Strain of Streptomyces lincolnensis L-427
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In this study, lincomycin A (Lin-A), a lincosamide antibiotic primarily synthesized by Streptomyces lincolnensis, was selected as a model to demonstrate a combined genetic regulation and process engineering strategy for production improvement. The GntR-family ... ...
