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Access to Fused Indolines with a Quaternary N, N'-Aminal Center: Aza-Wacker-Type Cyclization for a Telescoped Reaction Sequence

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A highly efficient one-pot sequence has been developed for the rapid construction of fused polycyclic indolines bearing a C2-N,N'-aminal quaternary center. The process, which employs 1,2-diaza-1,3-dienes and 2-substituted indoles as key substrates, proceeds t... ...