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TRPC6 Mediates Neuronal Hyperexcitability in the Lateral Habenula to Drive Trigeminal Neuralgia-Associated Anxiety

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Persistent facial and oral discomfort, particularly trigeminal neuralgia (TN), is frequently accompanied by anxiety, which has been closely linked to increased excitability of neurons in the lateral habenula (LHb). However, the mechanisms underlying this hyper... ...