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Disruption of gastrointestinal pdgfrα+ cells leads to loss of post-junctional inhibitory motor responses

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Fibroblast-like cells (FLCs) exist in the smooth muscle layers of visceral organs, yet in many instances their functional role(s) have not been identified. FLCs express platelet-derived growth factor receptor (PDGFR) α and are a novel class of excitable cells... ...