首页 正文

Enantioselective Synthesis of Functionalized 2,2-Disubstituted Piperidines Enabled by Pd-Catalyzed Decarboxylative Asymmetric Allylic Alkylation

{{output}}
Herein, we report a palladium-catalyzed decarboxylative asymmetric allylic alkylation (Pd-DAAA) for the synthesis of enantioenriched 2,2-disubstituted piperidines. This method efficiently constructs aza-quaternary stereocenters with high enantioselectivity and... ...