Pharmacokinetic and pharmacodynamic results from a randomized controlled study with the GHSR blocker PF-5190457 in recently abstinent patients with alcohol use disorder
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Objective: Ghrelin and LEAP2 act via the growth hormone secretagogue receptor (GHSR), which modulates feeding, alcohol use, and endocrine and immune system function. The GHSR blocker PF-5190457 has potential as a novel pharmacoth... ...
