Engineering endoplasmic reticulum targeted metal-polyphenol curcumin nanomicelles for melanoma therapy
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Melanoma has a high incidence and mortality, and current therapies are limited. Here, we developed TCPC, an ER-targeted nanomedicine guided by omics analysis. It consists of curcumin-loaded PEG-PCL nanomicelles coated with a Tannic acid-Cu metal-polyphenol net... ...