Thrombospondin-1 Is a Contact Sensor Triggering Adhesion in T Cells and Platelets While Differentially Regulating 2D and 3D Motility in T Cells
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The regulation of cell adhesion and motility is poorly understood. The present study uncovers a mechanism by which cells sense the microenvironment and regulate adhesion and motility. The C-terminal of TSP-1 was found to sense cell contact, which triggered N-t... ...
