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Endoplasmic reticulum stress exacerbates ischemia-reperfusion-induced pulmonary endothelial barrier dysfunction by activating TXNDC5

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Introduction: Lung ischemia-reperfusion injury (LIRI)-a fatal complication following major surgery, trauma, or shock- is characterized by pulmonary endothelial barrier (PEB) dysfunction. Although thioredoxin domain-containing pro... ...