Structure-guided dissection of the genetic variations within human LPA locus and its role in the development of cardiovascular diseases
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Lipoprotein (a) [Lp(a)] is a highly heterogeneous lipoprotein particle promoting panvascular disease. Structurally, it consists of an LDL-like core covalently bound to apolipoprotein (a) [apo(a)]. Molecular determinants linking various genetic variants of apo(... ...
