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p57 increases immunotherapy efficacy by promoting cGAS-STING-mediated innate sensing in hepatocellular carcinoma

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Hyperactivation of the cell cycle in cancer cells suppresses antitumor immunity. The endogenous cyclin-dependent kinase inhibitor p57 is an important tumor suppressor and a potential therapeutic target for hepatocellular carcinoma (HCC). However, the immunomod... ...