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Investigation of the effect of encapsulating cisplatin with the active compound silibinin in PLGA polymeric nanoparticles on the HeLa cervical cancer cell line

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Cisplatin remains one of the most widely used chemotherapeutic agents, yet its clinical efficacy is limited by poor tumor selectivity, dose-dependent toxicity, and the development of resistance. Silibinin, a hydrophobic natural compound with antioxidant and an... ...