P450 Cyptide Synthase KwwB Catalyzes Trp-C5-Trp-N1 Cross-Linking and Accepts Diverse Precursor Peptides
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Cytochrome P450 enzymes install C-C, C-N, or C-O cross-links on the precursor peptides of ribosomally synthesized and post-translationally modified peptides (RiPPs). Here, we bioinformatically mapped P450 enzymes based on the known families. Through functional... ...