Contrasting roles of APE1 and APE2 in genome maintenance, cancer development, and therapeutic targeting
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Apurinic/apyrimidinic endonucleases - APE1 and APE2 are central to genome maintenance and the cellular DNA damage response, with expanding relevance in cancer biology. APE1 is the primary endonuclease in base excision repair and functions as a redox coactivato... ...
