Cerebrospinal fluid ctDNA clarifies clonal divergence: leptomeningeal flare of EGFR-mutant disease after switch to selpercatinib for acquired RET fusion
{{output}}
Liquid biopsy can expose spatially segregated resistance biology that is invisible to single-site tissue testing, particularly across the blood-brain barrier. We report how cerebrospinal fluid (CSF) circulating tumor DNA (ctDNA) clarified therapeutic direction... ...
