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Targeting CaMKIIδ Overcomes Therapy Resistance in Acute Myeloid Leukemia by Suppressing STAT3/CDK6/BCL-2 Survival Axis

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Relapse and therapy resistance remain major barriers to improving clinical outcomes in acute myeloid leukemia (AML), underscoring the need for actionable therapeutic targets. In this study, we identify calcium/calmodulin-dependent protein kinase II delta (CaMK... ...