Regulated degradation of KCC2, a potassium-chloride co-transporter required for synaptic transmission and neurodevelopment
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Neuronal function requires fine-tuned and coordinated activity of several ion channels and transporters. One member of this ensemble is the KCC2 potassium-chloride cotransporter. Because KCC2 expression is required for GABA-dependent inhibitory synaptic transm... ...
