Maintenance of Energy Metabolism Is an Integral Part of Plakophilin-2 and Desmosome Functions
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Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a familial cardiac disease associated with ventricular arrhythmias and an increased risk of sudden cardiac death. Alterations in the desmosome gene plakophilin-2 (PKP2) lead to compromised contractility... ...