Co-presence of classical scrapie but not classical Bovine Spongiform Encephalopathy in transmissions from Dutch sheep with atypical scrapie
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Two cases of atypical scrapie (AS) from Dutch sheep were passaged to WT mice and ovine and bovine prion protein (PrP) transgenic mice. Both AS isolates failed to transmit to WT mice but were successfully transmitted to ovine PrP transgenic Tg338 and Tg59 mice,... ...
