Targeting YAP-TEAD Interaction with Honokiol to Inhibit Melanoma Progression and Metastasis
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The Hippo-YAP/TEAD pathway plays a central role in melanoma progression by regulating tumor cell proliferation, survival, and migration. Using a NanoLuc Binary Technology (NanoBiT) protein-protein interaction assay, we screened honokiol-based small molecules a... ...