Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies
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Immunoglobulin E (IgE)-mediated immediate hypersensitivity reactions underlie most allergic responses and are characterized by rapid mast cell (MC) activation and the subsequent release of mediators. These processes have been studied in rodent models via IgE o... ...