LLDT-8 attenuates brain metastasis in non-small cell lung cancer via selective p53 activation
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Brain metastasis (BM) remains a leading cause of mortality in non-small cell lung cancer (NSCLC) owing to inadequate blood-brain barrier (BBB) penetration and therapy resistance. Here, we developed a brain-tropic A549-BrM2 subline that recapitulates aggressive... ...
