The Protean Nature of 14-3‑3 Proteins in G Protein-Coupled Receptor Signaling: Emphasizing Selectivity and Dynamic Interactions at the Neurokinin Receptor 3 Interface
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Recent models of GPCR signaling extend beyond the canonical paradigm of ligand-induced activation primarily mediated by G-proteins and β-arrestins. Indeed, the various outcomes of GPCR activation are precisely regulated by several factors, including GPCR-inte... ...