Zhimu-Huangbo ameliorates AQP4 depolarization in diabetic cognitive impairment rats by targeting the serum-derived exosomal TIMP3-mediated MMP9/β-DG pathway
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Aquaporin-4 (AQP4) depolarization-mediated glymphatic system (GS) dysfunction is a critical pathological mechanism in diabetic cognitive impairment (DCI). However, its underlying mechanism has not been clarified. The Zhimu-Huangbo (ZMHB) herb pair, a classic f... ...
