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Assessing the critical role of ceramide in the pathogenesis of Alzheimer's disease and its clinical significance

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Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-β (Aβ) deposition, tau hyperphosphorylation, and synaptic loss. Emerging evidence indicates that apolipoprotein E (APOE) polymorphism and dysregulated ceramide met... ...