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Tubastatin A alleviates post-resuscitation myocardial damage possibly via inhibiting GSDME-mediated pyroptosis and MLKL-mediated necroptosis in a porcine model of cardiac arrest

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Introduction: Global ischemia reperfusion (I/R) stimulation induced by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) triggers multiple forms of programmed cell death including pyroptosis and necroptosis, and further... ...